Martha’s paper is out!!!! This work will also be the cover of a future issue of Biochemistry 🙂 Well done Martha!

Cool collaboration with Bela Bode and Ricardo Czekster 

 

 

 

 

 

 

 

 

 

 

 

 

Preprint alert! Rebecca’s paper is under review on Access Microbiology describing our journey in the Antibiotics under our feet project.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Chris’ paper is online! Interested in disrupting biofilms, cyclic peptides and enzymology? This will be a nice read!

 

 

 

 

 

 

 

 

 

 

 

 

Great collaboration with Megan Bergkessel and Marcus Bischoff

 

 

 

 

 

 

Charlene wrote a super cool perspective on cyclic dipeptides and how they can be participating in the oral-gut-brain axis and influencing our health. Check it out here

 

 

 

 

Congratulations Emmajay for the paper accepted on Nature Communications Chemistry! Open access paper available here

Emmajay also wrote a blog post on the importance of the work 🙂

We have around 1013 bacteria living in our bodies, a number comparable to the amount of human cells we possess. This community of bacteria inhabiting us is called the microbiota. The human microbiota can contribute to development, outcome and response to treatment of various diseases including cancer, bacterial and viral infections.

Why do some bacteria cause disease and can “take over” environments that they wouldn’t normally occupy? How can we keep good bacteria around and get rid or control the problematic ones?

Our research combines enzymology, structural biology, chemical biology and microbiology to understand how bacteria produce and use cyclic peptides in interspecies and interkingdom warfare and/or cooperation. Our purpose is to generate novel drugs, probes, carriers, and technologies that will allow us to control and modulate bacterial populations.

Check out our paper on cyclodipeptide synthases! Awesome job Chris!